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IUI 人工受孕流程

人工受孕又可稱為人工授精 intrauterine insemination (簡稱IUI),透過生殖醫療技術將男性精子經過實驗室處理後,挑選出品質優良的精子,在女性排卵日時注入子宮腔內,精蟲須自行游到輸卵管末端與卵子結合。

Explanation of Intrauterine Insemination (IUI) Procedure

Suitable Candidates for IUI

Candidates for IUI can be categorized into male and female factors.

Male Candidates:

  • Sperm count ≥10 million per cc with normal motility and morphology

  • Sexual dysfunction or abnormal sexual function

  • Retrograde ejaculation

  • Congenital absence of the vas deferens

  • Poor sperm quality or chromosomal abnormalities in sperm

Female Candidates:

  • Women over 35 years old or with diminished ovarian reserve

  • Mild endometriosis

  • Irregular menstrual cycles

  • Mild tubal adhesions or partial tubal blockage

  • Unexplained infertility despite normal test results

IUI-related costs typically include:

  • Ovulation medication (oral or injectable)

  • Luteal phase support (e.g., progesterone)

  • Semen processing and insemination

  • Ultrasound scans

  • Blood hormone tests

人工受孕相關療程說明

人工受孕適用對象

適合做人工受孕的對象可以分為男性、女性來做更詳細的說明。

人工受孕適用對象:男性

  1. 精蟲數量每cc至少達1000萬,且活動力和正常型態比率正常
  2. 男性性功能障礙或異常
  3. 逆行性射精
  4. 輸精管缺損
  5. 精蟲品質不良、配偶精子存在染色體高風險者

人工受孕適用對象:女性

  1. 35歲以上或卵子庫存量減少的女性
  2. 輕微的子宮內膜異位症
  3. 月經週期不固定
  4. 輸卵管輕微粘黏或輕微阻塞
  5. 檢查後皆正常的不明原因不孕

人工受孕費用

人工受孕費用會包含針劑與藥劑的費用以及手術費用,例如:黃體加強藥物、精蟲處理與植入費、排卵針劑費用、超音波、血液荷爾蒙檢測費用等。

IUI Treatment Process

Step 1: Infertility evaluation

Step 2: Begin IUI cycle after evaluation

Step 3: On menstrual Day 1–3, visit clinic for blood draw and ultrasound → Start ovulation medication (return on Day 8 for monitoring)

Step 4: On Day 14, take ovulation trigger shot ~36 hours before insemination

Step 5: Begin progesterone supplementation (Day 21)

Step 6: Pregnancy test (Day 31)

Male Procedure:

  • Abstain for 3–4 days before insemination

  • Collect semen by masturbation in a sterile container

  • Sperm is washed and motile sperm selected for insemination

Female Procedure:

  • Take ovulation medications or injections

  • Monitor follicle growth with transvaginal ultrasound

  • Once follicles mature, receive a trigger shot

  • Return for IUI within a specified window (usually 36 hours after the shot)

人工受孕療程

Step 1 先做不孕檢查

Step 2 完成不孕檢查 >> 正式進入人工受孕療程

Step 3 Day 1 - Day 3 月經來時到院抽血照超音波 >> 開始打排卵針或口服排卵藥 ( Day 8 回診抽血照超音波 )

Step 4 Day 14  精蟲植入前約36小時打破卵針 >> 精蟲植入

Step 5 Day 21 使用黃體素

Step 6 Day 31 驗孕檢測

男性:人工受孕日前禁慾3~4天,以自慰的方法將精液放入無菌取精瓶內交由生殖中心洗滌,篩選出活動性較好的精蟲。

女性:配合服用排卵藥或打排卵針,藉由陰道超音波監測卵泡大小並且追蹤濾泡生長情況,待濾泡成熟即可打破卵針,約一天後來進行人工受孕,將精子注入子宮腔內。

Sample IUI Timeline (For Reference Only)

Day of Menstrual Cycle Procedure

Before cycle Initial infertility evaluation for both partners
Day 2–3 Begin treatment, baseline ultrasound and blood tests
Day 3–7 Take oral ovulation medications daily
Day 6–10 Receive ovulation injections as prescribed
Day 12 Return for ultrasound to monitor follicles
Day 12–13 Ovulation trigger shot (if follicles are mature)
Day 14 Semen collection and intrauterine insemination
Day 14–30 Luteal phase support (progesterone)
Day 31 Return to clinic for pregnancy test 

人工受孕流程時間表

每個人的人工授精療程略有不同,時間僅供參考,實際人工受孕流程依主治醫師醫囑而定。

療程前 夫妻至門診做檢查
月經第2-3天 回診,療程開始
月經第3-7天 每天服用口服排卵藥
月經第6-10天 依照醫囑在固定時間打排卵針
月經第12天 回診照超音波
月經第12-13天 追蹤濾泡成熟度,施打破卵針
月經第14天 先生取精,太太進行精蟲植入
月經第14-30天 依照醫囑服用黃體素
月經第31天 回診驗孕 

Comparison: IUI vs. IVF

IUI – Intrauterine Insemination In vivo fertilization)

Women with open fallopian tubes

Men with slightly low sperm count or motility issues

Procedure: Ovulation stimulation (oral/injection) → Ultrasound → Ovulation trigger shot → Semen collection → IUI → Luteal support → Pregnancy test

Pregnancy Rate: Around 20%

Cost: Relatively low 

IVF – In Vitro Fertilization (In vitro fertilization)

Women with low egg reserve, blocked fallopian tubes, or age >35

Men with poor semen quality or azoospermia

Couples with failed IUI cycles for more than 3 times

Procedure: Follicle monitoring → Egg retrieval → Sperm collection → Fertilization → Embryo transfer → Pregnancy test

Pregnancy Rate: Approximately 20%–80%, depending on individual factors

Cost: Significantly higher than IUI

Note: Sperm and egg must meet naturally inside the body Fertilization occurs directly in the lab

人工受孕與試管嬰兒差異比較

人工受孕 (IUI) 體內受精 適合族群

  • 女性的輸卵管尚能通暢
  • 男性精蟲數量較少,精蟲活動力較差
  • 施打排卵針或排卵藥→超音波檢查→施打破卵針→取精→人工受孕→補充黃體素→驗孕 ( 懷孕機率 約20% )

試管嬰兒 (IVF) 體外受精 適合族群

  • 女性卵子數量少或輸卵管阻塞等婦科問題,年齡已超過35歲
  • 男性精液品質差、無精症等
  • 已嘗試3次人工受孕仍未成功
  • 夫妻雙方術前檢查→監測卵泡→取卵→取精→體外受精→胚胎移植→驗孕 ( 懷孕機率 約20%~80% )

因為人工受孕還是需要精子和卵子自己相遇結合,相對於試管嬰兒,人工授精的費用相對便宜很多。