☀ What is Egg Donation?

Egg donation refers to using healthy eggs legally matched by a fertility center, allowing a couple to achieve their fertility goals through IVF treatment.

The main causes of female infertility include gynecological diseases, low AMH, ovarian dysfunction, or chemotherapy. Thanks to advances in reproductive medicine, women can now complete their family plans using donor eggs from healthy individuals.

Explanation of Egg Donation

For women over the age of 40, egg quality and quantity decline with age, sometimes reaching the point of near-total depletion. Additionally, women with hereditary diseases may not be able to use their own eggs. Therefore, egg donation is recommended for these groups of patients.

Who is Eligible for Egg Donation?

• Those with diminished ovarian function due to advanced age or unexplained reasons

• Those whose ovaries cannot develop normally due to congenital diseases

• Those who have lost ovulatory function or respond poorly to stimulation due to infections, surgery, autoimmune conditions, or chemotherapy

• Those with genetic diseases who cannot use preimplantation genetic testing (PGT-M/PGD)

• Those who repeatedly failed to retrieve good-quality eggs/embryos, or had very few eggs retrieved

Egg Donation Sources

Egg donors come from egg banks, where the average donor age is around 26, and all donors pass strict health and genetic screening, including chromosomal tests, to ensure high-quality eggs.

Egg Bank vs. Fresh Eggs

Egg banks offer both frozen and fresh eggs. Frozen eggs are stored in liquid nitrogen at -196°C after retrieval and thawed for fertilization once matched, with matching typically taking only 1–2 weeks because of the existing database. Fresh eggs are retrieved on the day of donation and fertilized immediately with the husband's sperm. Although matching can take 3–4 months, insemination and further treatment can proceed on the same day.

Egg Bank (Frozen Eggs) 

1. Matching Time 1–2 weeks
2. Number of Donated Eggs Depending on treatment plan 
3. Success Rate Leading clinics report IVF success rates up to 80%

Fresh Eggs

1. Matching Time 3–4 months
2. Number of Donated Eggs Depending on treatment plan 
3. Success Rate Leading clinics report IVF success rates up to 80% 

How Much Does Egg Donation Cost?

The cost is generally around NT$300,000–400,000. For patients of advanced age or with extremely low egg reserves, who otherwise would need multiple egg retrievals, egg donation can actually be more affordable compared to repeated IVF with their own eggs, saving time and improving success rates. In other words, egg donation may help you realize the dream of parenthood more quickly.

Egg Donation Process

Regulations differ by country.

In Taiwan, once a couple agrees to undergo egg donation IVF, they must submit the husband's "fourth-degree kinship chart," the wife's "second-degree direct kinship data," and related documents to proceed with egg matching.

After successful matching, the couple will undergo health screenings (for women: hormone blood tests, ultrasound, hysteroscopy, etc.; for men: semen analysis). If any issues affecting pregnancy are found, the physician will address them surgically or with medication to maximize success. Once all preparations are complete, the wife will begin IVF treatment, which proceeds similarly to standard IVF.

Egg Matching and IVF Process (Example Flow)

(The actual process may vary based on each case)

Step 1: Egg Matching

• Infertility clinic consultation

  • Physician consultation

  • Blood tests (HIV, syphilis, blood type for both partners)

  • Semen analysis for husband

• Obtain an artificial reproduction diagnosis certificate

• Submit required documents:

  • Two copies of both spouses' national ID (front & back)

  • Husband's fourth-degree kinship chart (within one year)

  • Wife's second-degree kinship data (within one year)

  • If either spouse is a foreign national: family tree, declaration, notarized marriage certificate

  • Passports and national ID

  • If the foreign spouse holds a Taiwan ID, still must submit kinship documents at the Household Registration Office

  • IVF consent form

  • Egg donation consent form

  • Blood type reports for both partners

• Wait for match

  • Coordinator will inform you of the match results

  • The couple should maintain a healthy lifestyle while waiting

• After a successful match

  • Coordinator will inform you

  • Payment made

  • National Health Administration's fourth-degree kinship review

• Return visit

  • Health screenings for wife (hormone tests, hysterosalpingography, hysteroscopy, etc.)

  • Complete egg donation notarization

  • Husband freezes sperm for backup (if needed)

Step 2: IVF Using Donated Eggs

a. Using eggs from the egg bank

• Submit notarized documents

• Fertilize eggs to culture Day-5 blastocysts

• Depending on the case, may perform PGT-A (preimplantation genetic screening); results take about 1 month

• Report first day of menstrual cycle

• From day 2–3 of period, begin medications

• On day 11–12, check endometrial thickness

• On day 18–20, embryo transfer

• Return 14 days later for pregnancy test

b. Using fresh donor eggs

• Donor begins egg stimulation on day 3 of period

• Husband freezes sperm for backup

• Submit notarized documents

• On donor's egg retrieval day, husband provides fresh sperm to the IVF center

• Fertilize eggs to culture Day-5 blastocysts

• Depending on the case, may perform PGT-A; results take about 1 month

• Report first day of menstrual cycle

• From day 3 of period, begin medications

• On day 11–12, check endometrial thickness

• On day 18–20, embryo transfer

• Return 14 days later for pregnancy test

借卵意旨選擇生殖中心合法配對之健康卵子，夫妻可透過試管嬰兒療程達成生育需求。

造成婦女不孕症主要因素為婦科疾病、AMH 偏低、卵巢功能異常和化學藥物治療等等，如今受惠生殖醫學進步可透過"借卵療程"，以她人健康卵子完成生育計畫。

借卵說明

超過40歲高齡婦女，隨著年紀的增長除了卵子的品質下降，卵子也逐漸衰減甚至接近無卵的狀況；或因遺傳疾病無法使用自己的卵子，因此建議此不孕患者族群使用捐卵者提供的卵子來進行生育。

借卵注意事項一起看！

借卵適用族群

• 因高齡或不明原因，造成卵巢功能衰退者
• 卵巢因先天疾病無法正常發育者
• 因感染、手術、免疫因素、化學藥物治療，導致喪失排卵功能或刺激排卵反應不佳者
• 遺傳性疾病且無法以胚胎著床前遺傳診斷(PGT-M/PGD)協助者
• 多次取卵都無法取得品質良好的卵子/胚胎或取卵數過少者

捐贈卵子的來源

醫院擁有自己的卵子銀行，捐贈者平均年齡26歲且通過高規格的檢查，除了符合國健署的要求之外，更增加染色體篩查，確保受贈卵子的高品質。

卵子銀行VS新鮮卵子

茂盛醫院的卵子銀行分為冷凍卵子與新鮮卵子兩種，冷凍卵子為取卵後放置-196°C的液態氮裡冷凍保存，配對成功後再解凍受精，因已建立基本資料庫，配對時間只需 1~2 週；新鮮卵子則是捐卵者當日取卵後，直接與先生的精子結合受精，雖配對時間達3至4個月，但當日即可進行人工受孕下一步療程。

卵子銀行 (冷凍卵子) 

配對時間 約1~2週
借卵顆數 依借卵顆數不同而定
借卵顆數 依個案需求選擇 
成功率 優秀醫院借卵試管懷孕率高達 80%

新鮮卵子 

配對時間 3-4個月
借卵顆數 依療程次數不同而定
借卵顆數 依捐卵者取出卵子數而定
成功率 優秀醫院借卵試管懷孕率高達 80%

借卵費用怎麼算？

借卵費用約落在30~40萬之間。對於高齡或卵子量極低的患者，因為需多次取卵，借卵整體費用跟使用自己卵子的試管嬰兒療程比較起來反而低廉許多，不但節省時間，成功率也提高許多，只要轉念借卵能讓您更快實現為人父母的夢想。

借卵流程

確認接受借卵試管嬰兒療程，受贈夫妻需要繳交先生「四親等親屬關聯表」、受術妻「二親等直系關聯資料」及相關文件，進入卵子配對環節。

配對成功後，本院會安排受贈夫妻進行身體檢查（女性：荷爾蒙血液檢查、超音波檢查、子宮鏡檢查等；男性：精液分析）。若檢查出影響懷孕的因素，醫師會先採用手術或藥物排除，以提升成功懷孕率。當一切前置步驟都完成，受贈妻子將開始試管嬰兒療程，其過程與一般試管嬰兒療程雷同。

借卵第一步：卵子配對

不孕症門診領取診斷證明書繳交相關文件等待配對配對成功回診

Step 1. 不孕科門診

• 醫師諮詢
• 血液檢查（夫妻雙方的愛滋、梅毒、血型）
• 先生做精液檢查

Step 2. 領取診斷證明書

• 至諮詢室申請人工生殖診斷證明書

Step 3. 繳交同意借卵相關文件

• 夫妻身分證正反影本各二份
• 夫「一年內四親等親屬關聯表」
• 妻「一年內二親等直系關聯資料」
• 若一方為外籍人士，需另附：樹狀圖、切結書、經地方辦事處公證之結婚證明
• 夫妻雙證件（護照及身分證）
• 若外籍人士持有台灣身分證，則仍需至戶政事務所申請親屬資料
• 試管嬰兒同意書
• 受卵同意書
• 雙方血型檢查報告

Step 4. 等待配對

• 等待專員通知配對結果

• 受贈夫妻調整日程作息，維持健康生活習慣

Step 5. 配對成功

• 專員通知借卵配對結果

• 繳付費用

• 等待國健署四親等查核

Step 6. 回診

• 受贈妻子做身體檢查（賀爾蒙檢查、輸卵管攝影檢查、子宮鏡檢查等項目）

• 完成受卵公證

• 先生凍精備用（依情況而定）

借卵第二步：試管嬰兒

使用卵子庫存 (冷凍卵子) 者

Step 1. 使用卵子庫

• 繳交公證本
• 卵子受精培養成D5囊胚
• 依個案狀況，可能會進行PGT-A(PGS胚胎著床前染色體篩檢)，等待PGT-A報告結果約一個月

Step 2. 準備植入

• 回報月經週期第1天
• 月經第2-3天起，服用藥物
• 月經第11~12天，回診檢查子宮內膜厚度

Step 3. 胚胎植入

• 月經第18-20天，胚胎植入

• 植入後14天回診驗孕

使用新鮮卵子者

Step 1. 捐卵者療程

• 捐卵者月經第3天起進入捐卵療程
• 先生凍精備用
• 繳交公證本

Step 2. 先生取精

• 捐卵者取卵
• 捐卵者取卵當日，先生收集新鮮精子送至2F生殖中心
• 卵子受精培養成D5囊胚
• 依個案狀況，可能會進行PGT-A（PGS胚胎著床前染色體篩檢），等待PGT-A報告結果約一個月

Step 3. 準備植入

• 回報月經週期第1天
• 月經第3天起，服用藥物
• 月經第11-12天，回診檢查子宮內膜厚度

Step 4. 胚胎植入

• 月經第18-20天，胚胎植入
• 植入後14天回診驗孕

☀ What is Sperm Donation?

Sperm donation refers to selecting healthy sperm legally matched by a fertility center, allowing a legally married couple to achieve their fertility goals through IVF treatment.

According to the 2021 Assisted Reproductive Technology Report from Taiwan's National Health Administration, 9.6% of men are unable to conceive naturally due to severe infertility or genetic disorders and require IVF treatment to fulfill their dream of having children.

The report noted that among 49,652 IVF cycles, 322 cycles used donated sperm, making sperm donation an option for infertile couples.

Sperm Donation Considerations

Who is eligible for sperm donation in Taiwan?

• Patients with azoospermia (no sperm)

• Those with chromosomal abnormalities

• Those with hereditary diseases who, even after genetic testing, cannot produce healthy offspring

Source of Donated Sperm

Mau Medical Center has established a sperm bank, storing sperm in liquid nitrogen at -196°C. The bank offers both sperm donation and sperm reception services to help infertile couples successfully achieve pregnancy.

Every sperm donor must pass a series of health checks beyond standard semen analysis to qualify, including:

• Complete blood count, ABO blood type

• Hepatitis B/C

• Syphilis, HIV, gonorrhea, chlamydia

• Genetic disorders such as thalassemia

• Advanced screening for spinal muscular atrophy

• Fragile X syndrome

• Full karyotype chromosomal testing

Strict Screening Standards: Every sperm donor at Mau Medical Center undergoes not only standard examinations but also advanced chromosomal testing and detailed semen analysis. Only those who fully pass these rigorous evaluations are accepted as donors.

Cryopreservation Guarantee: Donated sperm is preserved at -196°C in liquid nitrogen. With current technology, thawed sperm maintains nearly the same quality as fresh sperm.

High-Quality IVF Technology: Mau Medical Center has over 40 years of experience in reproductive medicine, with a strong medical research team continuously refining assisted reproduction techniques. It also holds the highest number of IVF cycles performed in Taiwan, according to the National Health Administration.

Sperm Donation: A Path to Parenthood

Some couples have tried to conceive for many years without success, despite multiple gynecological check-ups showing no issues. It was only after visiting an infertility clinic for joint evaluation that they discovered male-factor infertility.

In some cases of mild male infertility, patients can still try assisted reproductive techniques to achieve pregnancy. However, in other cases where no usable sperm can be collected despite various retrieval methods, couples typically have three options: giving up, adopting, or pursuing sperm donation.

Some patients initially worry that using donated sperm might affect their bond with the child. However, in practice, these couples often feel the same joy and excitement as any expectant parents, and they cherish their child even more because of the challenges they have overcome.

Taiwan Sperm Donation Costs and Required Documents

Couples undergoing sperm donation must submit the wife's fourth-degree kinship form, the husband's second-degree direct kinship data, and other related documents.

After entering the sperm-matching process and achieving a match, the hospital will arrange health examinations for the wife, including hormone testing, blood tests, hysterosalpingography, and hysteroscopy. If any conditions that may affect pregnancy are detected, the physician will address them surgically or with medication to improve the chances of success. Once preparations are complete, the wife will begin IVF treatment.

Sperm Donation Process

Step 1: Infertility Clinic Visit

• Physician consultation

• Blood tests (HIV, syphilis, blood type for both spouses)

• Obtain consent forms

Step 2: Submit Documents

• Photocopies (front and back) of both spouses' ID cards

• Wife's fourth-degree kinship form

• Husband's second-degree kinship form

• Proof of marriage

• IVF consent form

• Blood type test reports for both spouses

Step 3: Wait for Matching

• Wait for notification from the consultation office

• Wife should maintain a healthy lifestyle while waiting

Step 4: Match Completed

• Consultation office notifies about the sperm donation match

• Await National Health Administration's fourth-degree kinship verification

• Wife undergoes health checks (hormone tests, hysterosalpingography, hysteroscopy, etc.)

• Finalize notarization of the sperm donation consent form

Step 5: IVF Treatment at Medical Center

借精意指選擇生殖中心配對之健康精子，合法夫妻將可透過試管療程達成生育需求。根據國健署發佈的110年人工生殖施行結果報告中，9.6%男性因嚴重不孕症或遺傳性疾病無法順利生育，需要藉由進行試管嬰兒療程才能如願。

報告指出49,652例試管嬰兒週期數中，其中有322個周期數使用受贈精子進行試管嬰兒療程，借精生子成為不孕症夫婦的選項！

借精注意事項

台灣借精條件有哪些？

• 無精症患者
• 染色體異常者
• 帶有家族遺傳疾病，經基因診斷仍無法生下健康子代者

捐贈精子的來源

茂醫院成立精子銀行，將精子完善保存在零下196℃的液態氮內，提供精子捐贈和精子受贈的服務，以協助不孕症夫婦順利生育。

每位捐精者除精液分析檢查外，另須經過以下健康檢查項目符合資格者才得以捐精。

• 血液常規檢查、ABO血型
• B/C型肝炎
• 梅毒、愛滋病、淋病、披衣菌
• 遺傳性疾病 海洋性貧血
• 高階檢查 脊髓肌肉萎縮症
• X染色體脆折症
• 全染色體核型檢查

1. 嚴格把關捐精男孩的素質：每個來到茂盛醫院的捐精男孩都會經過高規格的身體檢查，除了一般的常規檢查，茂盛醫院也讓每位捐精男孩做染色體檢查以及精密的精液分析。只有全數檢查都通過的捐精男孩才能在茂盛醫院精子銀行捐精。
2. 冷凍技術的保障：捐精男孩的精子會完好保存在零下196℃的液態氮內。目前的技術已經可以做到冷凍精卵在解凍之後品質跟新鮮精卵非常相似。
3. 優質的試管嬰兒技術：茂盛在人工生殖領域已深耕近40年以上，除了有堅強的醫療研究團隊不斷精進人工生殖技術，也是全台灣試管嬰兒週期數最多的醫療院所（國健署人工生殖施行結果報告）。

借精生子也是求子出路

有些夫婦備孕多年都沒有結果，期間也到婦科門診檢查多次都沒發現問題，直到來到不孕症門診夫妻雙方一起做檢查後，才第一次知道有男性不孕症的問題。有些夫婦在確診男性不孕症之後，因病情程度較輕，還有機會通過人工生殖療程及輔助受孕技術來協助懷孕。但，有些夫婦通過不同取精技術都無法收集足夠的適用精子，通常只有三種選擇：放棄有孩子、領養小孩以及借精療程。
有些患者在療程初期會擔心接受精子受贈會影響父母對孩子的感情，但事實是這些患者在療程和懷孕過程中也是跟一般父母一樣能夠感受迎接新生命的喜悅，反而會因為這是得來不易的過程而更加珍惜這段緣分。 

台灣借精費用與繳交文件

借精受贈夫妻需要繳交受術妻「四親等親屬關聯表」、先生「二等親直系關聯資料」及相關文件。

進入精子配對環節並配對成功後，本院會安排受贈妻子進行身體檢查，如：賀爾蒙、血液檢查、輸卵管攝影和子宮鏡等等，以手術或藥物排除影響懷孕的因素，提升成功懷孕率。當前置步驟完成後，受贈妻子將開始試管嬰兒療程。

借精療程這樣走！

Step 1 不孕科門診

• 醫師諮詢
• 血液檢查（夫妻雙方的愛滋、梅毒、血型）
• 領取同意書

Step 2 繳交文件

• 夫妻身分證正反影本各一份
• 妻「四親等親屬關聯表」
• 夫「直系二親等直系關聯表」
• 婚姻證明
• 試管嬰兒同意書
• 雙方血型檢查報告

Step 3 等待配對

• 等待諮詢室通知借精配對結果
• 受贈妻子調整日程作息，維持健康生活習慣

Step 4 配對完成

• 諮詢室通知借精人工受孕配對結果
• 等待國健署四親等查核
• 受贈妻子做身體檢查（賀爾蒙檢查、輸卵管攝影檢查、子宮鏡檢查等項目）
• 已公證「精子受贈同意書」

Step 5 茂盛醫院

• 試管嬰兒療程