IUI 人工受孕流程
人工受孕又可稱為人工授精 intrauterine insemination (簡稱IUI),透過生殖醫療技術將男性精子經過實驗室處理後,挑選出品質優良的精子,在女性排卵日時注入子宮腔內,精蟲須自行游到輸卵管末端與卵子結合。
Explanation of Intrauterine Insemination (IUI) Procedure
Suitable Candidates for IUI
Candidates for IUI can be categorized into male and female factors.
1. Male Candidates:
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Sperm count ≥10 million per cc with normal motility and morphology
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Sexual dysfunction or abnormal sexual function
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Retrograde ejaculation
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Congenital absence of the vas deferens
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Poor sperm quality or chromosomal abnormalities in sperm
2. Female Candidates:
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Women over 35 years old or with diminished ovarian reserve
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Mild endometriosis
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Irregular menstrual cycles
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Mild tubal adhesions or partial tubal blockage
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Unexplained infertility despite normal test results
IUI-related costs typically include:
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Ovulation medication (oral or injectable)
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Luteal phase support (e.g., progesterone)
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Semen processing and insemination
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Ultrasound scans
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Blood hormone tests
人工受孕相關療程說明
人工受孕適用對象
適合做人工受孕的對象可以分為男性、女性來做更詳細的說明。
人工受孕適用對象:男性
- 精蟲數量每cc至少達1000萬,且活動力和正常型態比率正常
- 男性性功能障礙或異常
- 逆行性射精
- 輸精管缺損
- 精蟲品質不良、配偶精子存在染色體高風險者
人工受孕適用對象:女性
- 35歲以上或卵子庫存量減少的女性
- 輕微的子宮內膜異位症
- 月經週期不固定
- 輸卵管輕微粘黏或輕微阻塞
- 檢查後皆正常的不明原因不孕
人工受孕費用
人工受孕費用會包含針劑與藥劑的費用以及手術費用,例如:黃體加強藥物、精蟲處理與植入費、排卵針劑費用、超音波、血液荷爾蒙檢測費用等。
IUI Treatment Process
Step 1: Infertility evaluation
Step 2: Begin IUI cycle after evaluation
Step 3: On menstrual Day 1–3, visit clinic for blood draw and ultrasound → Start ovulation medication (return on Day 8 for monitoring)
Step 4: On Day 14, take ovulation trigger shot ~36 hours before insemination
Step 5: Begin progesterone supplementation (Day 21)
Step 6: Pregnancy test (Day 31)
Male Procedure:
Abstain for 3–4 days before insemination
Collect semen by masturbation in a sterile container
Sperm is washed and motile sperm selected for insemination
Female Procedure:
Take ovulation medications or injections
Monitor follicle growth with transvaginal ultrasound
Once follicles mature, receive a trigger shot
Return for IUI within a specified window (usually 36 hours after the shot)
人工受孕療程
Step 1 先做不孕檢查
Step 2 完成不孕檢查 >> 正式進入人工受孕療程
Step 3 Day 1 - Day 3 月經來時到院抽血照超音波 >> 開始打排卵針或口服排卵藥 ( Day 8 回診抽血照超音波 )
Step 4 Day 14 精蟲植入前約36小時打破卵針 >> 精蟲植入
Step 5 Day 21 使用黃體素
Step 6 Day 31 驗孕檢測
男性:人工受孕日前禁慾3~4天,以自慰的方法將精液放入無菌取精瓶內交由生殖中心洗滌,篩選出活動性較好的精蟲。
女性:配合服用排卵藥或打排卵針,藉由陰道超音波監測卵泡大小並且追蹤濾泡生長情況,待濾泡成熟即可打破卵針,約一天後來進行人工受孕,將精子注入子宮腔內。
Sample IUI Timeline (For Reference Only)
Before cycle: Initial infertility evaluation for both partners
Day 2–3: Begin treatment, baseline ultrasound and blood tests
Day 3–7: Take oral ovulation medications daily
Day 6–10: Receive ovulation injections as prescribed
Day 12: Return for ultrasound to monitor follicles
Day 12–13: Ovulation trigger shot (if follicles are mature)
Day 14: Semen collection and intrauterine insemination
Day 14–30: Luteal phase support (progesterone)
Day 31: Return to clinic for pregnancy test
人工受孕流程時間表
每個人的人工授精療程略有不同,時間僅供參考,實際人工受孕流程依主治醫師醫囑而定。
療程前 夫妻至門診做檢查
月經第2-3天 回診,療程開始
月經第3-7天 每天服用口服排卵藥
月經第6-10天 依照醫囑在固定時間打排卵針
月經第12天 回診照超音波
月經第12-13天 追蹤濾泡成熟度,施打破卵針
月經第14天 先生取精,太太進行精蟲植入
月經第14-30天 依照醫囑服用黃體素
月經第31天 回診驗孕
Comparison: IUI vs. IVF
IUI – Intrauterine Insemination In vivo fertilization)
Women with open fallopian tubes
Men with slightly low sperm count or motility issues
Procedure: Ovulation stimulation (oral/injection) → Ultrasound → Ovulation trigger shot → Semen collection → IUI → Luteal support → Pregnancy test
Pregnancy Rate: Around 20%
Cost: Relatively low
IVF – In Vitro Fertilization (In vitro fertilization)
Women with low egg reserve, blocked fallopian tubes, or age >35
Men with poor semen quality or azoospermia
Couples with failed IUI cycles for more than 3 times
Procedure: Follicle monitoring → Egg retrieval → Sperm collection → Fertilization → Embryo transfer → Pregnancy test
Pregnancy Rate: Approximately 20%–80%, depending on individual factors
Cost: Significantly higher than IUI
Note: Sperm and egg must meet naturally inside the body Fertilization occurs directly in the lab
人工受孕與試管嬰兒差異比較
人工受孕 (IUI) 體內受精 適合族群
- 女性的輸卵管尚能通暢
- 男性精蟲數量較少,精蟲活動力較差
- 施打排卵針或排卵藥→超音波檢查→施打破卵針→取精→人工受孕→補充黃體素→驗孕 ( 懷孕機率 約20% )
試管嬰兒 (IVF) 體外受精 適合族群
- 女性卵子數量少或輸卵管阻塞等婦科問題,年齡已超過35歲
- 男性精液品質差、無精症等
- 已嘗試3次人工受孕仍未成功
- 夫妻雙方術前檢查→監測卵泡→取卵→取精→體外受精→胚胎移植→驗孕 ( 懷孕機率 約20%~80% )
因為人工受孕還是需要精子和卵子自己相遇結合,相對於試管嬰兒,人工授精的費用相對便宜很多。