IUI 人工受孕流程

人工受孕又可稱為人工授精 intrauterine insemination (簡稱IUI)，透過生殖醫療技術將男性精子經過實驗室處理後，挑選出品質優良的精子，在女性排卵日時注入子宮腔內，精蟲須自行游到輸卵管末端與卵子結合。

Explanation of Intrauterine Insemination (IUI) Procedure

Suitable Candidates for IUI

Candidates for IUI can be categorized into male and female factors.

1. Male Candidates:

• Sperm count ≥10 million per cc with normal motility and morphology

• Sexual dysfunction or abnormal sexual function

• Retrograde ejaculation

• Congenital absence of the vas deferens

• Poor sperm quality or chromosomal abnormalities in sperm

2. Female Candidates:

• Women over 35 years old or with diminished ovarian reserve

• Mild endometriosis

• Irregular menstrual cycles

• Mild tubal adhesions or partial tubal blockage

• Unexplained infertility despite normal test results

IUI-related costs typically include:

• Ovulation medication (oral or injectable)

• Luteal phase support (e.g., progesterone)

• Semen processing and insemination

• Ultrasound scans

• Blood hormone tests

IUI Treatment Process

Step 1: Infertility evaluation

Step 2: Begin IUI cycle after evaluation

Step 3: On menstrual Day 1–3, visit clinic for blood draw and ultrasound → Start ovulation medication (return on Day 8 for monitoring)

Step 4: On Day 14, take ovulation trigger shot ~36 hours before insemination

Step 5: Begin progesterone supplementation (Day 21)

Step 6: Pregnancy test (Day 31)

Male Procedure:

• Abstain for 3–4 days before insemination

• Collect semen by masturbation in a sterile container

• Sperm is washed and motile sperm selected for insemination

Female Procedure:

• Take ovulation medications or injections

• Monitor follicle growth with transvaginal ultrasound

• Once follicles mature, receive a trigger shot

• Return for IUI within a specified window (usually 36 hours after the shot)

Sample IUI Timeline (For Reference Only)

• Before cycle: Initial infertility evaluation for both partners

• Day 2–3: Begin treatment, baseline ultrasound and blood tests
• Day 3–7: Take oral ovulation medications daily
• Day 6–10: Receive ovulation injections as prescribed
• Day 12: Return for ultrasound to monitor follicles
• Day 12–13: Ovulation trigger shot (if follicles are mature)
• Day 14: Semen collection and intrauterine insemination
• Day 14–30: Luteal phase support (progesterone)
• Day 31: Return to clinic for pregnancy test 

Comparison: IUI vs. IVF

IUI – Intrauterine Insemination In vivo fertilization)

Women with open fallopian tubes

Men with slightly low sperm count or motility issues

Procedure: Ovulation stimulation (oral/injection) → Ultrasound → Ovulation trigger shot → Semen collection → IUI → Luteal support → Pregnancy test

Pregnancy Rate: Around 20%

Cost: Relatively low 

IVF – In Vitro Fertilization (In vitro fertilization)

Women with low egg reserve, blocked fallopian tubes, or age >35

Men with poor semen quality or azoospermia

Couples with failed IUI cycles for more than 3 times

Procedure: Follicle monitoring → Egg retrieval → Sperm collection → Fertilization → Embryo transfer → Pregnancy test

Pregnancy Rate: Approximately 20%–80%, depending on individual factors

Cost: Significantly higher than IUI

Note: Sperm and egg must meet naturally inside the body. Fertilization occurs directly in the lab